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7 Risk Factors to Speed up Uremia

7 Risk Factors to Speed up Uremia
The following are 7 risk factors. Without attention, they can ad insult to injury, and speed up the progression to uremia. Hope you attach importance as early as possible.

1. Proteinuria

Large amounts of proteinuria can accelerate the progression of chronic kidney damage. This is because renal tubular epithelial cells cannot absorb protein excessively. If urine protein is excreted more, it can cause protein cast in renal tubule to block renal tubule, and lead to local ischemia and atrophy of renal tubule, and glomerular shrinkage and collapse. In addition, large amounts of proteinuria also activate inflammatory cells in renal tubular interstitial cells, leading to inflammatory responses and interstitial fibrosis. So it is important to delay the deterioration of renal function.

2. Diabetes

Poor blood sugar control also aggravates kidney damage. In the early stage, urine protein can be increased, and in severe cases, blood creatinine can be increased. Diet control, moderate exercises, and medications can help lower blood sugar level, and it is suggested to choose insulin treatment timely.

3. High blood pressure

Strict control of blood pressure is the most important measure to intervene in the progression of chronic kidney disease and reduce mortality. And avoid reducing blood pressure too fast or too low. The target blood pressure should be controlled between 110-130/70-80mmhg. For the selection of drugs, the first choice is ACEI/ARB with renal protective effect, or combination diuretics, calcium channel blockers, αand βreceptor blocker, as well as vasodilator substance. In terms of medication methods, try to choose long-acting preparations, that is, once a day, to enhance compliance.

4. Nephrotoxic drugs

In patients with chronic renal impairment, drug elimination is slow and drug accumulation is easy. In addition, patients with chronic renal failure are often accompanied by hypoalbuminemia and severe anemia, so they have increased susceptibility to drugs, and drug concentrations in blood and tissues can easily reach toxic levels.

5. pH and electrolyte disturbance

When kidney function is damaged, metabolic waste and water retain in blood, resulting in imbalance of acid and alkali. It should be promptly corrected.

6. Infections

Kidney patients often have poor physical condition and immunity, so they are prone to infections, such as respiratory tract infection, skin infections, fungal infection, etc. Infections can aggravate kidney disease.

7. Obesity and others

Obese person should control weight, and anemia, hypercalcemia, liver failure and heart failure should be given corresponding targeted treatment.

Therefore, patients with chronic kidney disease (CKD) should focus on the early detection and prevention, as well as the treatment of underlying causes so as to prevent kidney tissues from being damaged. For more information on kidney disease treatment, please leave a message below or contact online doctor.

Tag: Kidney Failure Kideny Failure Basics
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